A rare genetic disorder, sometimes called "tuberous sclerosis complex", that is characterized by the growth of numerous noncancerous (benign) tumors that are most commonly seen in the brain, eyes, kidneys, heart, lungs and skin though any part of the body can be affected. Symptoms can range from mild to severe, depending on the size or location of the overgrowth. The condition often affects the brain, causing seizures, behavioral problems such as hyperactivity and aggression, and intellectual disability or learning problems. Some children have the characteristic features of autism spectrum disorder, a developmental disorder that affects communication and social interaction. Benign brain tumors can also develop in people with tuberous sclerosis complex and some can cause serious or life-threatening complications.

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